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pentobarbital will reduce the level or result of tacrolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.pentobarbital will lower the extent or impact of atogepant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Encouraged atogepant dosage with concomitant use of robust or a